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January 2021 marked a grim milestone in the COVID-19 pandemic, with over two million people dead. Since the new strain of coronavirus (SARS-CoV-2) emerged on the global stage in early 2020, an historical and unprecedented effort has been deployed to quell this global health crisis. As we settle into a new year with increased optimism following the successful development of vaccines against COVID-19, we are turning our sights toward the future, with critical policy questions in mind.