The Lancet is an independent, international weekly general medical journal founded in 1823 by Thomas Wakley. Since its first issue (October 5, 1823), the journal has strived to make science widely available so that medicine can serve, and transform society, and positively impact the lives of people. The Lancet is committed to applying scientific knowledge to improve health and advance human progress. In our weekly issues, and online first content, we publish some of the best science from the best scientists worldwide, providing an unparalleled global reach and impact on health.

The Lancet has grown from a 19th century pamphlet to a high impact, international journal. The Lancet is proud to have published papers that have made a crucial contribution to science and human health. View a selection of our research landmarks from more than 10 000 published issues.