The WIREs publications focus on high-profile research areas at the interfaces of the traditional disciplines.
Content for each WIREs title is selected, invited, and reviewed by an internationally renowned Editorial Board, ensuring that the highest scientific and presentational standards are maintained. Coverage is carefully crafted to provide an encyclopedic coverage of the field. New and updated reviews are added every month, ensuring that the most current information in the field is always available. Reviews are highly structured and consistently formatted, maximizing the accessibility and utility of the content to the user. The WIREs combine the most powerful features of online review journals (high online visibility, immediacy, full abstracting and indexing) with the traditional strengths of the encyclopedic reference model (structure, authority, and comprehensiveness of coverage). A built-in mechanism for updating previously published content further differentiates the WIREs from traditional review journals.

With their deliberate focus on high-impact topics at the interfaces of the traditional research fields, together with a strong emphasis on interdisciplinary outreach at the level of the individual article, the WIREs offer a valuable new forum for cross-disciplinary communication in scientific and scholarly research.